Dementia ASR Screening

Overview The Dementia ASR Screening & Multi-Factorial Risk Stratification Application is an advanced digital health portal designed to bridge the gap between AI-driven speech biomarkers and modifiable clinical risk factors. Built on a premium, mobile-first dark theme interface, the portal enables patients to undergo non-invasive, visual speech elicitation tests in seconds, generating comprehensive, weighted dementia conversion risk assessments. Key Features & Technological Innovation Lossless Acoustic Elicitation: Features a custom-built, client-side Web Audio API recorder that encodes raw microphone samples directly into lossless 16-bit Mono PCM WAV format. This ensures 100% processing compatibility with cloud-based Automatic Speech Recognition engines. Speechmatics SaaS ASR Integration: Orchestrates advanced speech analyses via Express backend proxies. By disabling disfluency filtering (remove_disfluencies: false), the portal natively captures and tags spoken filler words. Acoustic Pause Biomarker Extraction: Reads word-level transcript timestamps to automatically isolate and flag long conversational hesitation gaps exceeding 1.5 seconds, a key marker in acoustic cognitive screens. Wiley 2025 Multi-Factorial Stratification: Incorporates a validated clinical risk algorithm based on the October 2025 study in Alzheimer's & Dementia (DOI: 10.1002/alz.70870): Age Scoring, Cognitive Reserve, BMI,Depression Screening (PHQ-2), Weighted Clinical Risk Dial: Automatically weighs Vocal speech biomarkers (40% weight) against Clinical modifiable factors (60% weight) to render a composite, color-coded Stratified Risk Indicator (Low, Moderate, or High Risk). Comprehensive Session Review Timeline: Connects to a self-healing SQLite database to store serialized disfluency details, allowing patients to inspect past tests and review historical reports exactly as they looked live along with an Interactive Demographics Editor.