
Overview The Dementia ASR Screening & Multi-Factorial Risk Stratification Application is an advanced digital health portal designed to bridge the gap between AI-driven speech biomarkers and modifiable clinical risk factors. Built on a premium, mobile-first dark theme interface, the portal enables patients to undergo non-invasive, visual speech elicitation tests in seconds, generating comprehensive, weighted dementia conversion risk assessments. Key Features & Technological Innovation Lossless Acoustic Elicitation: Features a custom-built, client-side Web Audio API recorder that encodes raw microphone samples directly into lossless 16-bit Mono PCM WAV format. This ensures 100% processing compatibility with cloud-based Automatic Speech Recognition engines. Speechmatics SaaS ASR Integration: Orchestrates advanced speech analyses via Express backend proxies. By disabling disfluency filtering (remove_disfluencies: false), the portal natively captures and tags spoken filler words. Acoustic Pause Biomarker Extraction: Reads word-level transcript timestamps to automatically isolate and flag long conversational hesitation gaps exceeding 1.5 seconds, a key marker in acoustic cognitive screens. Wiley 2025 Multi-Factorial Stratification: Incorporates a validated clinical risk algorithm based on the October 2025 study in Alzheimer's & Dementia (DOI: 10.1002/alz.70870): Age Scoring, Cognitive Reserve, BMI,Depression Screening (PHQ-2), Weighted Clinical Risk Dial: Automatically weighs Vocal speech biomarkers (40% weight) against Clinical modifiable factors (60% weight) to render a composite, color-coded Stratified Risk Indicator (Low, Moderate, or High Risk). Comprehensive Session Review Timeline: Connects to a self-healing SQLite database to store serialized disfluency details, allowing patients to inspect past tests and review historical reports exactly as they looked live along with an Interactive Demographics Editor.
19 May 2026