Our team built an agent-driven Healthcare Safety Platform designed to arrest James Regen’s “Swiss-cheese” iatrogenic cascades by unifying disparate hospital data into a Databricks Lakehouse and surfacing real-time risk insights. We began by defining the problem scope—10 percent of inpatients suffer preventable harm when latent system flaws align with active errors—then organized our work around four specialized personas. Agentic Maya Thompson led a strategic analysis of EHR admission/discharge records, incident and near-miss logs, and staffing schedules to prioritize the failure modes that most undermine patient safety and throughput. Carlos Reyes ingested data streams from EHRs, medical devices, wearables, and clinical protocols via Auto Loader into Bronze, Silver, and Gold Delta tables, codified transformation logic in Delta Live Tables, and enforced data governance with Unity Catalog to ensure compliance and lineage traceability. Dr. Priya Singh developed and rigorously validated predictive models—combining lab values, time-series vitals, protocol deviation flags, and staffing ratios—to flag patients at highest risk of cascading harm, audited model fairness across units, and registered top-performing versions in MLflow. Finally, Olivia Chen translated complex risk scores and incident trends into an intuitive dashboard using Databricks SQL and an embedded React interface, designing sliding-scale gauges, alert workflows tied to staff schedules, and drill-down incident timelines that guide timely, targeted interventions. Over multiple iterations, the team tagged each other on data-readiness checks, schema clarifications, feature requests, and prototype refinements in our integrated chat system, converging on a production-ready solution that continuously monitors care pathways, predicts misalignment in advance, and closes the “holes” in our clinical defenses—turning fragmented hospital data into life-saving insights.