biologyAI

Bioinformatics is a new type of science where scientists study biology using vast databases of DNA and protein sequence, protein structure, and many other kinds of data. We propose to develop a new AI system to help bioinformaticians study cancer by using an LLM to extract data from scientific abstract. For this project specifically we are looking at a new platform to cure cancer, Bispecific T-Cell Engagers (BiTEs), that has a potential to be applicable to a wide variety of cancers. We designed a AI chatbot to help bioinformatics researchers search for suitable antigens for specific cancers that could be targets of the BiTEs. For this demo, we prove out our idea by searching for antigens of uveal melanoma, the first cancer that was treated by this method using the drug Tebentafusp. We limit our search to before 2000 so as to be before any potential development of Tebentafusp.